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Issue 7, 2016
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Antibodies as stratagems against cancer

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Abstract

Antibodies have been in the frontline of anticancer research during the last few decades, since a number of different ways have been discovered to utilize them as parts or main components of anticancer drugs. Antibodies are used as the only component of some anticancer drugs, but they can also be conjugated with a variety of substances. Antibody engineering methods such as humanization, chimerization and Fc engineering are applied in order to modify their properties according to the requirements of anticancer drug application. Given the continuous advances in biology and informatics, the role of antibodies in anticancer treatment is expected to be prominent.

Graphical abstract: Antibodies as stratagems against cancer

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Publication details

The article was received on 20 Oct 2015, accepted on 11 Dec 2015 and first published on 11 Dec 2015


Article type: Review Article
DOI: 10.1039/C5MB00699F
Citation: Mol. BioSyst., 2016,12, 2047-2055
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    Antibodies as stratagems against cancer

    L. Papageorgiou, N. T. Cuong and D. Vlachakis, Mol. BioSyst., 2016, 12, 2047
    DOI: 10.1039/C5MB00699F

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