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Issue 8, 2016

Controlled assembly of heterotypic cells in a core–shell scaffold: organ in a droplet

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Abstract

This paper reports a droplet-based microfluidic approach to fabricate a large number of monodisperse, portable microtissues, each in an individual drop. We use water–water–oil double emulsions as templates and spatially assemble hepatocytes in the core and fibroblasts in the shell, forming a 3D liver model in a drop.

Graphical abstract: Controlled assembly of heterotypic cells in a core–shell scaffold: organ in a droplet

Supplementary files

Article information


Submitted
20 Feb 2016
Accepted
10 Mar 2016
First published
10 Mar 2016

Lab Chip, 2016,16, 1346-1349
Article type
Communication

Controlled assembly of heterotypic cells in a core–shell scaffold: organ in a droplet

Q. Chen, S. Utech, D. Chen, R. Prodanovic, J. Lin and D. A. Weitz, Lab Chip, 2016, 16, 1346 DOI: 10.1039/C6LC00231E

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