Jump to main content
Jump to site search

Issue 2, 2016
Previous Article Next Article

Synthetic microfluidic paper: high surface area and high porosity polymer micropillar arrays

Author affiliations

Abstract

We introduce Synthetic Microfluidic Paper, a novel porous material for microfluidic applications that consists of an OSTE polymer that is photostructured in a well-controlled geometry of slanted and interlocked micropillars. We demonstrate the distinct benefits of Synthetic Microfluidic Paper over other porous microfluidic materials, such as nitrocellulose, traditional paper and straight micropillar arrays: in contrast to straight micropillar arrays, the geometry of Synthetic Microfluidic Paper was miniaturized without suffering capillary collapse during manufacturing and fluidic operation, resulting in a six-fold increased internal surface area and a three-fold increased porous fraction. Compared to commercial nitrocellulose materials for capillary assays, Synthetic Microfluidic Paper shows a wider range of capillary pumping speed and four times lower device-to-device variation. Compared to the surfaces of the other porous microfluidic materials that are modified by adsorption, Synthetic Microfluidic Paper contains free thiol groups and has been shown to be suitable for covalent surface chemistry, demonstrated here for increasing the material hydrophilicity. These results illustrate the potential of Synthetic Microfluidic Paper as a porous microfluidic material with improved performance characteristics, especially for bioassay applications such as diagnostic tests.

Graphical abstract: Synthetic microfluidic paper: high surface area and high porosity polymer micropillar arrays

Back to tab navigation

Supplementary files

Article information


Submitted
23 Oct 2015
Accepted
19 Nov 2015
First published
20 Nov 2015

Lab Chip, 2016,16, 298-304
Article type
Paper
Author version available

Synthetic microfluidic paper: high surface area and high porosity polymer micropillar arrays

J. Hansson, H. Yasuga, T. Haraldsson and W. van der Wijngaart, Lab Chip, 2016, 16, 298
DOI: 10.1039/C5LC01318F

Social activity

Search articles by author

Spotlight

Advertisements