Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 2, 2016
Previous Article Next Article

Optofluidic FRET lasers using aqueous quantum dots as donors

Author affiliations


An optofluidic FRET (fluorescence resonance energy transfer) laser is formed by putting FRET pairs inside a microcavity acting as a gain medium. This integration of an optofluidic laser and the FRET mechanism provides novel research frontiers, including sensitive biochemical analysis and novel photonic devices, such as on-chip coherent light sources and bio-tunable lasers. Here, we investigated an optofluidic FRET laser using quantum dots (QDs) as FRET donors. We achieved lasing from Cy5 as the acceptor in a QD–Cy5 pair upon excitation at 450 nm, where Cy5 has negligible absorption by itself. The threshold was approximately 14 μJ mm−2. The demonstrated capability of QDs as donors in the FRET laser greatly improves the versatility of optofluidic laser operation due to the broad and large absorption cross section of the QDs in the blue and UV spectral regions. The excitation efficiency of the acceptor molecules through a FRET channel was also analyzed, showing that the energy transfer rate and the non-radiative Auger recombination rate of QDs play a significant role in FRET laser performance.

Graphical abstract: Optofluidic FRET lasers using aqueous quantum dots as donors

  • This article is part of the themed collection: Optofluidics
Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Aug 2015, accepted on 30 Nov 2015 and first published on 01 Dec 2015

Article type: Paper
DOI: 10.1039/C5LC01004G
Citation: Lab Chip, 2016,16, 353-359

  •   Request permissions

    Optofluidic FRET lasers using aqueous quantum dots as donors

    Q. Chen, A. Kiraz and X. Fan, Lab Chip, 2016, 16, 353
    DOI: 10.1039/C5LC01004G

Search articles by author