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Issue 3, 2016
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Experimental and numerical studies on standing surface acoustic wave microfluidics

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Abstract

Standing surface acoustic waves (SSAW) are commonly used in microfluidics to manipulate cells and other micro/nano particles. However, except for a simple one-dimensional (1D) harmonic standing waves (HSW) model, a practical model that can predict particle behaviour in SSAW microfluidics is still lacking. Herein, we established a two-dimensional (2D) SSAW microfluidic model based on the basic theory in acoustophoresis and our previous modelling strategy to predict the acoustophoresis of microparticles in SSAW microfluidics. This 2D SSAW microfluidic model considers the effects of boundary vibrations, channel materials, and channel dimensions on the acoustic propagation; as an experimental validation, the acoustophoresis of microparticles under continuous flow through narrow channels made of PDMS and silicon was studied. The experimentally observed motion of the microparticles matched well with the numerical predictions, while the 1D HSW model failed to predict many of the experimental observations. Particularly, the 1D HSW model cannot account for particle aggregation on the sidewall in PDMS channels, which is well explained by our 2D SSAW microfluidic model. Our model can be used for device design and optimization in SSAW microfluidics.

Graphical abstract: Experimental and numerical studies on standing surface acoustic wave microfluidics

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Publication details

The article was received on 23 Jun 2015, accepted on 21 Aug 2015 and first published on 24 Dec 2015


Article type: Paper
DOI: 10.1039/C5LC00707K
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Citation: Lab Chip, 2016,16, 515-524
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    Experimental and numerical studies on standing surface acoustic wave microfluidics

    Z. Mao, Y. Xie, F. Guo, L. Ren, P. Huang, Y. Chen, J. Rufo, F. Costanzo and T. J. Huang, Lab Chip, 2016, 16, 515
    DOI: 10.1039/C5LC00707K

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