Issue 84, 2016
From the journal:

Chemical Communications

A conformation and charge co-modulated ultrasensitive biomimetic ion channel†

Sheng-Lin Cai,a   Yu-Bin Zheng,a   Shuo-Hui Cao,ab   Xiu-Hong Caia  and  Yao-Qun Li*a  

* Corresponding authors

a Department of Chemistry and Key Laboratory of Analytical Sciences, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, P. R. China
E-mail: yaoqunli@xmu.edu.cn

b Department of Electronic Science, Xiamen University, Xiamen, P. R. China

Abstract

For the first time, a biomimetic ion channel co-modulated simultaneously by conformation and charge using a single stimulus has been demonstrated, and, based on the synergetic effect of this channel, an ultrasensitive nanopore sensor for ATP with a limit of detection down to sub-pM was developed.

Graphical abstract: A conformation and charge co-modulated ultrasensitive biomimetic ion channel

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Article information

DOI
https://doi.org/10.1039/C6CC04899D
Article type
Communication
Submitted
12 Jun 2016
Accepted
23 Sep 2016
First published
26 Sep 2016

Chem. Commun., 2016,52, 12450-12453

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A conformation and charge co-modulated ultrasensitive biomimetic ion channel

S. Cai, Y. Zheng, S. Cao, X. Cai and Y. Li, Chem. Commun., 2016, 52, 12450 DOI: 10.1039/C6CC04899D

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