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Issue 29, 2016
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A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates

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Abstract

Spontaneous electron transport to molecular oxygen led to regeneration of oxidised nicotinamide cofactor in cell lysates that contain an alcohol dehydrogenase, a quinone reductase and a quinone mediator. This concept allows the efficient oxidation of alcohols in the presence of alcohol dehydrogenase-containing E. coli lysates and catalytic amounts of the quinone lawsone.

Graphical abstract: A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates

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Publication details

The article was received on 11 Jan 2016, accepted on 15 Mar 2016 and first published on 15 Mar 2016


Article type: Communication
DOI: 10.1039/C5CC10316A
Citation: Chem. Commun., 2016,52, 5198-5201
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    A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates

    J. Haas, M. A. Schätzle, S. M. Husain, J. Schulz-Fincke, M. Jung, W. Hummel, M. Müller and S. Lüdeke, Chem. Commun., 2016, 52, 5198
    DOI: 10.1039/C5CC10316A

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