Calix[8]arene nanoreactor for Cu(i)-catalysed C–S coupling†
Abstract
The catalytic activity of Cu(I) confined within a phenanthroline-containing calix[8]arene derivative was tested in C–S cross-coupling reactions. The substrate selectivity, solvent dependence, and catalyst loading differ significantly from those reported for bimetallic molecular systems. The putative monomeric complex represents the first calix[8]arene functionalised for endo-oriented metal chelation used as a nanoreactor.