In this work, we developed a novel light-up nanocluster beacon (NCB) based on shuttling dark silver nanoclusters (NCs) to a bright scaffold through hybridization. The fluorescence enhancement was as high as 70-fold when the two templates were on the opposite sides of the duplexes, enabling sensitive and selective detection of DNA.
Y. Teng, X. Jia, S. Zhang, J. Zhu and E. Wang, Chem. Commun., 2016, 52, 1721 DOI: 10.1039/C5CC09138A
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