Synthesis, characterization and in vitro biocompatibility assessment of a novel tripeptide hydrogelator, as a promising scaffold for tissue engineering applications

Abstract

We have synthesized and characterized a self-assembling tripeptide hydrogelator Ac-L-Phe-L-Phe-L-Ala-NH₂. A series of experiments showed that the hydrogel material could serve as a stabile and biocompatible physical support as it improves the survival of HEK293T cells in vitro, thus being a promising biomaterial for use in tissue engineering applications.