Issue 2, 2016

Hydrogen peroxide-responsive micelles self-assembled from a peroxalate ester-containing triblock copolymer

Abstract

A novel ABA triblock copolymer by using peroxalate esters as linkages was synthesized. In water, this amphiphilic copolymer self-assembled into micelles which were used as drug delivery carriers. When stimulated with hydrogen peroxide, the micelles disassembled to release drugs since the responsive peroxalate ester linkages would be cleaved after the reaction with hydrogen peroxide.

Graphical abstract: Hydrogen peroxide-responsive micelles self-assembled from a peroxalate ester-containing triblock copolymer

Supplementary files

Article information

Article type
Communication
Submitted
17 Sep 2015
Accepted
05 Dec 2015
First published
14 Dec 2015

Biomater. Sci., 2016,4, 255-257

Author version available

Hydrogen peroxide-responsive micelles self-assembled from a peroxalate ester-containing triblock copolymer

C. Liu, X. Zhu, X. Wang, D. Miao, X. Liang, C. Wang, L. Pang, H. Sun, D. Kong and J. Yang, Biomater. Sci., 2016, 4, 255 DOI: 10.1039/C5BM00391A

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