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Issue 33, 2016
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Paper-based sperm DNA integrity analysis

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Abstract

We demonstrate a rapid, sensitive, and low cost paper-based approach for sperm chromatin integrity analysis that quantifies both DNA fragmentation and packaging. The paper-based test provides identical clinical outcome as the gold standard sperm chromatin structure assay. This technology is fast, simple, and suitable for broad application in clinics.

Graphical abstract: Paper-based sperm DNA integrity analysis

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Publication details

The article was received on 25 May 2016, accepted on 20 Jul 2016 and first published on 26 Jul 2016


Article type: Communication
DOI: 10.1039/C6AY01506A
Citation: Anal. Methods, 2016,8, 6260-6264
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    Paper-based sperm DNA integrity analysis

    R. Nosrati, M. M. Gong, M. C. San Gabriel, A. Zini and D. Sinton, Anal. Methods, 2016, 8, 6260
    DOI: 10.1039/C6AY01506A

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