Jump to main content
Jump to site search

Issue 3, 2016
Previous Article Next Article

Synthesis and characterization of a multimode stationary phase: Congo red derivatized silica in nano-flow HPLC

Author affiliations

Abstract

A novel Congo red (CR) derivatized silica stationary phase was prepared and packed into a fused silica capillary tube for nano-flow HPLC. A variety of analytes including poly-aromatic hydrocarbons, parabens, acids, sulfonamides, bases, and nucleosides were successfully separated using the CR. In comparison with commercial ODS columns, this new stationary phase has a different separation mechanism (hydrophobically-assisted ion-exchange), which was evident in the separation of benzoic acid derivatives and sulfonamides. The successful application of CR-bonded silica stationary phase in the HILIC and PALC modes demonstrates the effectiveness of this potential chromatographic material in nano flow HPLC.

Graphical abstract: Synthesis and characterization of a multimode stationary phase: Congo red derivatized silica in nano-flow HPLC

Back to tab navigation

Supplementary files

Article information


Submitted
30 Sep 2015
Accepted
21 Nov 2015
First published
08 Dec 2015

Analyst, 2016,141, 1083-1090
Article type
Paper
Author version available

Synthesis and characterization of a multimode stationary phase: Congo red derivatized silica in nano-flow HPLC

Y. Zhang, Y. Zhang, G. Wang, W. Chen, P. He and Q. Wang, Analyst, 2016, 141, 1083
DOI: 10.1039/C5AN02021B

Social activity

Search articles by author

Spotlight

Advertisements