Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery†
With inspirations from natural viruses, arginine-containing dendritic lipopeptides were designed for bioinspired fabrication. Self-assembling the defined amphiphilic lipopeptides generated virus-inspired nanovectors with an arginine-rich corona. These nanovectors provided some remarkable benefits for gene delivery, including well-defined nanostructure, high transfection efficiency, serum resistance and low cytotoxicity.
- This article is part of the themed collection: 2015 Journal of Materials Chemistry B Hot Papers