Facile and controlled synthesis of stable water-soluble cupric sulfide quantum dots for significantly inhibiting the proliferation of cancer cells

Wei Shuang; Xiaobing Wang; Ge Wang; Yuming Guo; Kui Wang; Gai Yang; Lin Zhu; Lin Yang

doi:10.1039/C5TB00960J

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Facile and controlled synthesis of stable water-soluble cupric sulfide quantum dots for significantly inhibiting the proliferation of cancer cells†

Wei Shuang,^a Xiaobing Wang,^a Ge Wang,^a Yuming Guo,*^a Kui Wang,^a Gai Yang,^a Lin Zhu^a and Lin Yang*^a

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* Corresponding authors

^a Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. China
E-mail: yanglin1819@163.com
Fax: +86 373 3328507
Tel: +86 373 3325058

Abstract

Amorphous and crystalline copper sulfide quantum dots (QDs) with good water-solubility were obtained controllably by a novel hydrolysis strategy. These QDs exhibited anti-proliferation activities on cancer cells rather than normal cells and the biological activities are related to their polymorphs. Our study opens up new avenues for fabricating stable water-soluble metal sulfide QDs.

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DOI: https://doi.org/10.1039/C5TB00960J
Article type: Communication
Submitted: 20 May 2015
Accepted: 03 Jun 2015
First published: 04 Jun 2015

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J. Mater. Chem. B, 2015,3, 5603-5607

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Facile and controlled synthesis of stable water-soluble cupric sulfide quantum dots for significantly inhibiting the proliferation of cancer cells

W. Shuang, X. Wang, G. Wang, Y. Guo, K. Wang, G. Yang, L. Zhu and L. Yang, J. Mater. Chem. B, 2015, 3, 5603 DOI: 10.1039/C5TB00960J

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Journal of Materials Chemistry B

Facile and controlled synthesis of stable water-soluble cupric sulfide quantum dots for significantly inhibiting the proliferation of cancer cells†

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Facile and controlled synthesis of stable water-soluble cupric sulfide quantum dots for significantly inhibiting the proliferation of cancer cells

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