Issue 122, 2015

A colorimetric and ultrasensitive immunosensor for one-step pathogen detection via the combination of nanoparticle-triggered signal amplification and magnetic separation

Abstract

We develop a visual immunosensor for the one-step detection of Salmonella enterica by using gold nanoparticle triggered enzyme signal amplification and magnetic separation. This immunosensor shows an enhanced sensitivity compared with an enzyme-linked immunosorbent assay, without the involvement of any equipment, thus providing a promising platform for rapid and sensitive detection of pathogens.

Graphical abstract: A colorimetric and ultrasensitive immunosensor for one-step pathogen detection via the combination of nanoparticle-triggered signal amplification and magnetic separation

Supplementary files

Article information

Article type
Communication
Submitted
18 Oct 2015
Accepted
17 Nov 2015
First published
18 Nov 2015

RSC Adv., 2015,5, 100633-100637

Author version available

A colorimetric and ultrasensitive immunosensor for one-step pathogen detection via the combination of nanoparticle-triggered signal amplification and magnetic separation

Y. Chen and M. Xie, RSC Adv., 2015, 5, 100633 DOI: 10.1039/C5RA21727J

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