Issue 116, 2015
From the journal:

RSC Advances

Regioselective synthesis of triazoles via base-promoted oxidative cycloaddition of chalcones with azides in aqueous solution†

Wenchao Yang,a   Tao Miao,*a   Pinhua Lia  and  Lei Wang*ab  

* Corresponding authors

a Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, P. R. China
E-mail: leiwang@chnu.edu.cn
Fax: +86-561-309-0518
Tel: +86-561-380-2069

b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, P. R. China

Abstract

A base-promoted oxidative cycloaddition of chalcones with azides in aqueous solution has been developed under transition-metal-free conditions, which provides a green method for the regioselective synthesis of trisubstituted triazoles in good yields.

Graphical abstract: Regioselective synthesis of triazoles via base-promoted oxidative cycloaddition of chalcones with azides in aqueous solution

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Article information

DOI
https://doi.org/10.1039/C5RA16974G
Article type
Paper
Submitted
22 Aug 2015
Accepted
28 Oct 2015
First published
28 Oct 2015

RSC Adv., 2015,5, 95833-95839

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Regioselective synthesis of triazoles via base-promoted oxidative cycloaddition of chalcones with azides in aqueous solution

W. Yang, T. Miao, P. Li and L. Wang, RSC Adv., 2015, 5, 95833 DOI: 10.1039/C5RA16974G

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