Issue 109, 2015

Facile, novel and efficient synthesis of new pyrazolo[3,4-b]pyridine products from condensation of pyrazole-5-amine derivatives and activated carbonyl groups

Abstract

An efficient synthesis of novel ethyl-1,3,4-triphenyl-1H-pyrazolo[3,4-b]pyridine-6-carboxylate products has been achieved via condensation of pyrazole-5-amine derivatives and activated carbonyl groups, in refluxing acetic acid. This process has been found to be useful in the preparation of new N-fused heterocycle products in good to excellent yields.

Graphical abstract: Facile, novel and efficient synthesis of new pyrazolo[3,4-b]pyridine products from condensation of pyrazole-5-amine derivatives and activated carbonyl groups

Supplementary files

Article information

Article type
Paper
Submitted
19 Aug 2015
Accepted
13 Oct 2015
First published
13 Oct 2015

RSC Adv., 2015,5, 89652-89658

Author version available

Facile, novel and efficient synthesis of new pyrazolo[3,4-b]pyridine products from condensation of pyrazole-5-amine derivatives and activated carbonyl groups

A. Ghaedi, G. R. Bardajee, A. Mirshokrayi, M. Mahdavi, A. Shafiee and T. Akbarzadeh, RSC Adv., 2015, 5, 89652 DOI: 10.1039/C5RA16769H

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