Issue 93, 2015

Kinetic study of DNA hybridization on DNA-modified gold nanoparticles with engineered nano-interfaces

Abstract

Colorimetric DNA sensing systems using DNA-modified gold nanoparticles (GNPs) rely on DNA hybridization events on the GNP. We report a systematic study of DNA hybridization kinetics on GNPs with different surface modifications using probe DNA and different molecular weight PEGs. The DNA hybridization kinetics are extremely sensitive not only to probe DNA density but also to the molecular weight of PEG.

Graphical abstract: Kinetic study of DNA hybridization on DNA-modified gold nanoparticles with engineered nano-interfaces

Supplementary files

Article information

Article type
Communication
Submitted
06 Jul 2015
Accepted
01 Sep 2015
First published
02 Sep 2015

RSC Adv., 2015,5, 76014-76018

Author version available

Kinetic study of DNA hybridization on DNA-modified gold nanoparticles with engineered nano-interfaces

A. Takashima and M. Oishi, RSC Adv., 2015, 5, 76014 DOI: 10.1039/C5RA13116B

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