Issue 86, 2015

Benzothiazepines: chemistry of a privileged scaffold

Abstract

Benzothiazepines are one such class of heterocyclic scaffolds with celebrated biological activities. The flooding of the pharmaceutical market with cardiovascular drugs like diltiazem, clentiazem and siratiazem bearing the benzothiazepine core confirms the biological importance of the core. This review presents a comprehensive vision of the various synthetic tactics adopted till now to afford benzothiazepine cores.

Graphical abstract: Benzothiazepines: chemistry of a privileged scaffold

Article information

Article type
Review Article
Submitted
26 Jun 2015
Accepted
06 Aug 2015
First published
06 Aug 2015

RSC Adv., 2015,5, 70619-70639

Author version available

Benzothiazepines: chemistry of a privileged scaffold

D. Saha, G. Jain and A. Sharma, RSC Adv., 2015, 5, 70619 DOI: 10.1039/C5RA12422K

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