Novel textile material based disposable sensors for biomedical analysis

Abstract

A novel textile material was used for the design of new disposable stochastic sensors for biomedical analysis. The textile material used had a veil texture, and was plasma coated with a layer of silver; the sensing part was covered using a plasma technique with a second layer of carbon like diamond. The silver side was used as an electrical contact. The diamond side was modified with three types of maltodextrines having different dextrose equivalence (DE) (MD-1 (DE 4.0–7.0), MD-2 (DE 13.0–17.0), MD-3 (DE 16.5–19.5)). Interleukin-6 (IL-6), a pro-inflammatory cytokine that plays a key role in the pathophysiology of cardiovascular diseases, was used as a model analyte. These stochastic microsensors can be used reliably for both qualitative and quantitative analysis for the assay of IL-6 in whole blood samples with limits of determination as low as 1 fg mL⁻¹.