An efficient catalyst-free chemoselective multicomponent reaction for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives†
Abstract
An efficient method for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives has been developed via a catalyst-free, one-pot chemoselective multicomponent domino reaction. The method offers ease of execution, easy and column free separation, mild reaction conditions, and high yields.