Indium-catalyzed microwave-accelerated pot economic C–C bond formation process towards the ‘dry-media’ synthesis of pyrimidine derivatives

Abstract

An efficient pot and time economic ‘dry-media’ synthesis of pyrimidine core containing scaffolds by application of an indium triflate catalyzed carbon–carbon bond formation procedure through Diels–Alder reaction using microwaves is described. The method is associated with some attractive characteristics such as short reaction time, high yield of products, and recyclability of recovered catalyst from the reaction mixture.