SCHEDULED MAINTENANCE
Most direct alkynylation methods of trifluoromethyl ketones require an additional ligand. In this study, a simple, practical and efficient superbase system for the direct alkynylation of trifluoromethyl ketones was developed without any additional ligand. The catalytic system can tolerate a wide range of functional groups on ketones and alkynes.
L. Wang, N. Liu, B. Dai, X. Ma and L. Shi, RSC Adv., 2015, 5, 10089 DOI: 10.1039/C4RA14322A
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