Fluorogenic displacement biosensors for PSA detection using antibody-functionalised quantum dot nanoparticles

Abstract

Novel quantum dot conjugated immunosensors are presented for the accurate identification of seminal fluid in forensic casework. The production of a fluorescence signal upon the displacement of moderately bound quencher-labelled peptide analogues by Prostate Specific Antigen (PSA) overcomes many of the practical disadvantages associated with traditional lateral flow cartridge testing.