Issue 6, 2015
From the journal:

RSC Advances

One-pot synthesis of alkyl pyrrole-2-carboxylates starting from β-nitroacrylates and primary amines†

Alessandro Palmieri,*a   Serena Gabrielli,a   Marco Parlapianoa  and  Roberto Ballini*a  

* Corresponding authors

a Green Chemistry Group, School of Science and Technology, Chemistry Division, University of Camerino, via S. Agostino 1, 62032 Camerino, MC, Italy
E-mail: alessandro.palmieri@unicam.it, roberto.ballini@unicam.it
Fax: +39 0737 402297

Abstract

Herein, we present a new, efficient, one-pot synthesis of pyrrole-2-carboxylate derivatives starting from ketal-functionalized β-nitroacrylates in combination with primary amines under acidic heterogeneous conditions.

Graphical abstract: One-pot synthesis of alkyl pyrrole-2-carboxylates starting from β-nitroacrylates and primary amines

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Article information

DOI
https://doi.org/10.1039/C4RA13094D
Article type
Communication
Submitted
24 Oct 2014
Accepted
05 Dec 2014
First published
09 Dec 2014

RSC Adv., 2015,5, 4210-4213

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One-pot synthesis of alkyl pyrrole-2-carboxylates starting from β-nitroacrylates and primary amines

A. Palmieri, S. Gabrielli, M. Parlapiano and R. Ballini, RSC Adv., 2015, 5, 4210 DOI: 10.1039/C4RA13094D

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