Synthesis of water soluble polyrotaxanes by end-capping polypseudo-rotaxanes of γ-CDs with PHEMA-PPO-PEO-PPO-PHEMA using ATRP of MPC

Abstract

A twice ATRP protocol is developed for the preparation of water soluble single-chain stranded polyrotaxanes (PRs) by end-capping polypseudorotaxanes (PPRs) formed from γ-CDs with PHEMA-PPO-PEO-PPO-PHEMA using oligomers of MPC as a bulky stopper. It is shown that those threaded γ-CDs simultaneously reside on PHEMA and PEG segments to give access to both loose- and over-fit structured PR-based multi-block copolymers.