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Issue 23, 2015
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Advanced stimuli-responsive polymer nanocapsules with enhanced capabilities for payloads delivery

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Abstract

Stimuli-responsive polymer nanocapsules (PNCs) are smart nanocarriers that encapsulate functional payloads and release them on demand upon external triggers. Stimuli-responsive PNCs are of interest in a wide range of disciplines such as pharmaceutics, agriculture, and materials science. Studies on stimuli-responsive PNCs so far are widely reported but are mainly focused on using only one stimulus to release one payload. However, a nanocarrier is efficient if distinct payloads can be selectively released via different stimuli because unwanted and unspecific release can be avoided. Here, the recent progress of stimuli-responsive PNCs that possess enhanced capabilities for payloads delivery is highlighted, including PNCs that respond to multiple stimuli, stimuli-responsive PNCs that co-encapsulate different payloads, and stimuli-responsive PNCs that release the payloads selectively or in a pulsatile way. Finally, the possible future directions in this area are suggested.

Graphical abstract: Advanced stimuli-responsive polymer nanocapsules with enhanced capabilities for payloads delivery

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Publication details

The article was received on 04 Mar 2015, accepted on 31 Mar 2015 and first published on 14 Apr 2015


Article type: Review Article
DOI: 10.1039/C5PY00323G
Polym. Chem., 2015,6, 4197-4205
  • Open access: Creative Commons BY license
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    Advanced stimuli-responsive polymer nanocapsules with enhanced capabilities for payloads delivery

    Y. Zhao, L. Lv, S. Jiang, K. Landfester and D. Crespy, Polym. Chem., 2015, 6, 4197
    DOI: 10.1039/C5PY00323G

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      [Original citation] - Published by The Royal Society of Chemistry.

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