Issue 46, 2015

Synthesis of indoles and polycyclic amides via ruthenium(ii)-catalyzed C–H activation and annulation

Abstract

Ruthenium(II)-catalyzed oxidative coupling of NH protic amides with alkynes has been developed for the synthesis of a diversity of complex structures, such as N-acyl indole and tricyclic amide derivatives.

Graphical abstract: Synthesis of indoles and polycyclic amides via ruthenium(ii)-catalyzed C–H activation and annulation

Supplementary files

Article information

Article type
Paper
Submitted
26 Aug 2015
Accepted
15 Sep 2015
First published
17 Sep 2015

Org. Biomol. Chem., 2015,13, 11228-11234

Author version available

Synthesis of indoles and polycyclic amides via ruthenium(II)-catalyzed C–H activation and annulation

H. Lin, S. Li and L. Dong, Org. Biomol. Chem., 2015, 13, 11228 DOI: 10.1039/C5OB01788B

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