Issue 34, 2015

Novel insights into a major DNA oxidative lesion: its effects on Z-DNA stabilization

Abstract

Here, we have provided novel insights into the effects of 8-oxodG substitutions on B–Z transitions of CpG dinucleotide DNAs. A combination of different techniques including a CD study, a PAGE analysis, DFT calculations and molecular modeling has been collectively used.

Graphical abstract: Novel insights into a major DNA oxidative lesion: its effects on Z-DNA stabilization

Supplementary files

Article information

Article type
Communication
Submitted
02 Jul 2015
Accepted
27 Jul 2015
First published
28 Jul 2015

Org. Biomol. Chem., 2015,13, 8996-8999

Novel insights into a major DNA oxidative lesion: its effects on Z-DNA stabilization

J. Wang, S. Wang, C. Zhong, T. Tian and X. Zhou, Org. Biomol. Chem., 2015, 13, 8996 DOI: 10.1039/C5OB01340B

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