Changjiang Yang, Juanjuan Li, Rong Zhou, Xiangyu Chen, Yunpeng Gao and Zhengjie He
Org. Biomol. Chem., 2015,13, 4869-4878
DOI:
10.1039/C5OB00258C,
Paper
Novel spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines have been synthesized in good to excellent yields via the annulation reactions of the corresponding 3-alkylideneoxindoles and 3-alkylidenebenzofuranones with Huisgen zwitterions. The preliminary bioassay demonstrated that some of the spiropyrazolines possess good in vitro fungicidal activity against several crop fungi at a concentration of 50 μg mL−1.
