Issue 3, 2015
From the journal:

Organic & Biomolecular Chemistry

A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates†

Michael N. Gandy,a   Lindsay T. Byrneb  and  Keith A. Stubbs*a  

* Corresponding authors

a School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA 6009, Australia
E-mail: keith.stubbs@uwa.edu.au

b Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia

Abstract

A generalised, simple and efficient synthesis of N-acetyl-5-bromo-4-chloroindoxyl and related analogues required for the synthesis of indigogenic substrates to probe for biological activities is reported. The method is both synthetically and operationally simple and represents a significant improvement on existing methods.

Graphical abstract: A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates

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Article information

DOI
https://doi.org/10.1039/C4OB02248C
Article type
Paper
Submitted
22 Oct 2014
Accepted
10 Nov 2014
First published
10 Nov 2014

Org. Biomol. Chem., 2015,13, 905-908

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A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates

M. N. Gandy, L. T. Byrne and K. A. Stubbs, Org. Biomol. Chem., 2015, 13, 905 DOI: 10.1039/C4OB02248C

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