Issue 4, 2015
From the journal:

Organic & Biomolecular Chemistry

Gold-catalyzed spiro-N,O-ketal synthesis†

M. Grammatikopoulou,a   S. Thysiadisa  and  V. Sarli*a  

* Corresponding authors

a Faculty of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece
E-mail: sarli@chem.auth.gr

Abstract

An efficient method for the synthesis of spiro-N,O-ketals with 5- and 6-membered rings was developed via a gold-catalyzed spiroamidoketalization of alkynyl amidoalcohols under mild conditions. This methodology has been successfully applied to the synthesis of a spiro-N,O-ketal analogue of marineosin A.

Graphical abstract: Gold-catalyzed spiro-N,O-ketal synthesis

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4OB02050B
Article type
Paper
Submitted
26 Sep 2014
Accepted
17 Nov 2014
First published
17 Nov 2014

Org. Biomol. Chem., 2015,13, 1169-1178

Permissions

Request permissions

Gold-catalyzed spiro-N,O-ketal synthesis

M. Grammatikopoulou, S. Thysiadis and V. Sarli, Org. Biomol. Chem., 2015, 13, 1169 DOI: 10.1039/C4OB02050B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements