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Issue 42, 2015
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Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging

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Abstract

A chelator-free doping method is developed for constructing a Ni-integrated CuS nanostructure as a novel PA/MRI contrast agent. It exhibits tunable near-infrared absorption. Moreover, the hybrid nanostructure has demonstrated a dramatically enhanced T1 relaxivity compared with Ni ions. Due to these unique properties, chelator-free nanoparticles have been successfully applied for in vivo PA/MRI dual-modal imaging.

Graphical abstract: Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging

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Supplementary files

Article information


Submitted
04 Aug 2015
Accepted
19 Sep 2015
First published
30 Sep 2015

Nanoscale, 2015,7, 17631-17636
Article type
Communication
Author version available

Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging

D. Gao, P. Zhang, C. Liu, C. Chen, G. Gao, Y. Wu, Z. Sheng, L. Song and L. Cai, Nanoscale, 2015, 7, 17631
DOI: 10.1039/C5NR05237H

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