Synthesis and characterization of novel nanosilica molybdic acid and its first catalytic application in the synthesis of new and known pyranocoumarins

Abstract

Nanosilica molybdic acid (nano-SMA) was prepared and employed as a novel, recyclable and safe catalyst for the one-pot, three-component condensation of 4-hydroxycoumarin with aldehydes and malononitrile to produce new and known pyrano[2,3-c]chromenes as potent biologically active compounds. This novel method has many advantages, such as the high product yield and a simple work-up procedure.