Single step, high yield synthesis of para-hydroxy functionalized POCOP ligands and their Ni(ii) pincer derivatives

Abstract

The stoichiometric control of the reaction of phloroglucinol with different chlorophosphines ClPR₂, R = iPr (1), tBu (2) or Ph (3), leads to the direct and high yield synthesis of the p-hydroxy functionalized POCOP ligands [C₆H₃-5-OH-1,3-(OPR₂)₂]. Typical reactions of these compounds with NiCl₂·6H₂O provide a facile access to the corresponding POCOP pincer derivatives [NiCl{C₆H₂-4-OH-2,6-(OPR₂)₂}], R = iPr (4), tBu (5) or Ph (6).