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Issue 14, 2015
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Soft fluorescent nanomaterials for biological and biomedical imaging

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Abstract

Soft fluorescent nanomaterials have attracted recent attention as imaging agents for biological applications, because they provide the advantages of good biocompatibility, high brightness, and easy biofunctionalization. Here, we provide a survey of recent developments in fluorescent soft nano-sized biological imaging agents. Various soft fluorescent nanoparticles (NPs) (including dye-doped polymer NPs, semiconducting polymer NPs, small-molecule organic NPs, nanogels, micelles, vesicles, and biomaterial-based NPs) are summarized from the perspectives of preparation methods, structure, optical properties, and surface functionalization. Based on both optical and functional properties of the nano-sized imaging agents, their applications are then reviewed in terms of in vitro imaging, in vivo imaging, and cellular-process imaging, by means of specific or nonspecific targeting.

Graphical abstract: Soft fluorescent nanomaterials for biological and biomedical imaging

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Publication details

The article was received on 03 Sep 2014 and first published on 22 Dec 2014


Article type: Review Article
DOI: 10.1039/C4CS00294F
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Citation: Chem. Soc. Rev., 2015,44, 4699-4722
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    Soft fluorescent nanomaterials for biological and biomedical imaging

    H. Peng and D. T. Chiu, Chem. Soc. Rev., 2015, 44, 4699
    DOI: 10.1039/C4CS00294F

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