Issue 40, 2015

Rose Bengal incorporated in mesostructured silica nanoparticles: structural characterization, theoretical modeling and singlet oxygen delivery

Abstract

Rose Bengal (RB), a xanthene dye, incorporated into mesostructured silica nanoparticles (MSNs) exhibits efficient singlet oxygen (1O2) generation when illuminated with 540 nm green light which is particularly promising for PDT applications. Several systems with different RB loadings were synthesized and fully characterized by means of spectroscopic techniques in combination with a computational study, to optimize the amount of RB in order to avoid the formation of aggregates that is detrimental for a high 1O2 delivery.

Graphical abstract: Rose Bengal incorporated in mesostructured silica nanoparticles: structural characterization, theoretical modeling and singlet oxygen delivery

Supplementary files

Article information

Article type
Paper
Submitted
19 Jun 2015
Accepted
08 Sep 2015
First published
09 Sep 2015

Phys. Chem. Chem. Phys., 2015,17, 26804-26812

Author version available

Rose Bengal incorporated in mesostructured silica nanoparticles: structural characterization, theoretical modeling and singlet oxygen delivery

B. Martins Estevão, F. Cucinotta, N. Hioka, M. Cossi, M. Argeri, G. Paul, L. Marchese and E. Gianotti, Phys. Chem. Chem. Phys., 2015, 17, 26804 DOI: 10.1039/C5CP03564C

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