Jump to main content
Jump to site search

Issue 85, 2015
Previous Article Next Article

Controlling release, unfolding and dissociation of membrane protein complexes in the gas phase through collisional cooling

Author affiliations

Abstract

Mass spectrometry of intact membrane protein complexes requires removal of the detergent micelle by collisional activation. We demonstrate that the necessary energy can be obtained by adjusting the degree of collisional cooling in the ion source. This enables us to extend the energy regime for dissociation of membrane protein complexes.

Graphical abstract: Controlling release, unfolding and dissociation of membrane protein complexes in the gas phase through collisional cooling

Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Aug 2015, accepted on 03 Sep 2015 and first published on 03 Sep 2015


Article type: Communication
DOI: 10.1039/C5CC07045G
Author version
available:
Download author version (PDF)
Citation: Chem. Commun., 2015,51, 15582-15584
  •   Request permissions

    Controlling release, unfolding and dissociation of membrane protein complexes in the gas phase through collisional cooling

    M. Landreh, I. Liko, P. Uzdavinys, M. Coincon, J. T. S. Hopper, D. Drew and C. V. Robinson, Chem. Commun., 2015, 51, 15582
    DOI: 10.1039/C5CC07045G

Search articles by author

Spotlight

Advertisements