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Issue 22, 2015
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Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery

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Abstract

Polymeric vesicles constructed from cyclodextrin- and azobenzene-grafted poly(glycidyl methacrylate)s showed excellent stability owing to the multiple host–guest complexation. Upon culturing in Na2S2O4-contained buffer solution, cargo-loaded vesicles disassembled, for potential applications in colon-specific drug delivery.

Graphical abstract: Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery

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Article information


Submitted
22 Jan 2015
Accepted
09 Feb 2015
First published
10 Feb 2015

Chem. Commun., 2015,51, 4715-4718
Article type
Communication

Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery

W. Gu, Q. Li, H. Lu, L. Fang, Q. Chen, Y. Yang and H. Gao, Chem. Commun., 2015, 51, 4715
DOI: 10.1039/C5CC00628G

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