Intracellular Zn2+ detection with quantum dot-based FLIM nanosensors

Consuelo Ripoll; Miguel Martin; Mar Roldan; Eva M. Talavera; Angel Orte; Maria J. Ruedas-Rama

doi:10.1039/C5CC06676J

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Intracellular Zn²⁺ detection with quantum dot-based FLIM nanosensors†

Consuelo Ripoll,^a Miguel Martin,^b Mar Roldan,^b Eva M. Talavera,^a Angel Orte

*^a and Maria J. Ruedas-Rama

*^a

Author affiliations

* Corresponding authors

^a Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain
E-mail: angelort@ugr.es, mjruedas@ugr.es
Tel: +34-958243825

^b GENYO, Pfizer-University of Granada-Junta de Andalucia Centre for Genomics and Oncological Research, Avda Ilustracion 114, PTS, 18016 Granada, Spain

Abstract

Fluorescence Lifetime Imaging Microscopy (FLIM) has been employed for the detection of intracellular Zn²⁺ levels, implicated in various signalling pathways, using a family of quantum dot (QD) nanosensors. The sensing mechanism was based on photoinduced electron transfer (PET) between an azacycle receptor group and the QD nanoparticles.

Download options Please wait...

Supplementary files

Supplementary information PDF (1404K)

Article information

DOI: https://doi.org/10.1039/C5CC06676J
Article type: Communication
Submitted: 09 Aug 2015
Accepted: 29 Sep 2015
First published: 29 Sep 2015
This article is Open Access

Download Citation

Chem. Commun., 2015,51, 16964-16967

Author version available

Download author version (PDF)

Permissions

Request permissions

Intracellular Zn²⁺ detection with quantum dot-based FLIM nanosensors

C. Ripoll, M. Martin, M. Roldan, E. M. Talavera, A. Orte and M. J. Ruedas-Rama, Chem. Commun., 2015, 51, 16964 DOI: 10.1039/C5CC06676J

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications