Hybridization thermodynamics on solid supports are compared with those in solution for two types of hybridization probe, DNA and uncharged morpholino oligonucleotides of identical sequences. Trends in hybridization affinity are discussed with respect to ionic strength, temperature, and surface behavior.
W. Qiao, H. Chiang, H. Xie and R. Levicky, Chem. Commun., 2015, 51, 17245 DOI: 10.1039/C5CC06674C
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