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Issue 92, 2015
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Chemical labeling of intracellular proteins via affinity conjugation and strain-promoted cycloadditions in live cells

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Abstract

A versatile chemical labeling approach was developed, where intracellular proteins were first incorporated with a bioorthogonal group via affinity conjugation, and subsequently labeled via strain-promoted cycloaddition reactions in live cells.

Graphical abstract: Chemical labeling of intracellular proteins via affinity conjugation and strain-promoted cycloadditions in live cells

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The article was received on 24 Jun 2015, accepted on 18 Sep 2015 and first published on 18 Sep 2015


Article type: Communication
DOI: 10.1039/C5CC05208D
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Citation: Chem. Commun., 2015,51, 16537-16540
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    Chemical labeling of intracellular proteins via affinity conjugation and strain-promoted cycloadditions in live cells

    X. Chen, F. Li and Y. Wu, Chem. Commun., 2015, 51, 16537
    DOI: 10.1039/C5CC05208D

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