Issue 78, 2015

Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease

Abstract

The first total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease is described by native chemical ligation. Chemical synthesis of azide-labeled proteins would provide useful protein tools for biochemical, biophysical or medical studies.

Graphical abstract: Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease

Supplementary files

Article information

Article type
Communication
Submitted
11 Jun 2015
Accepted
03 Aug 2015
First published
03 Aug 2015

Chem. Commun., 2015,51, 14632-14635

Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease

Y. Qi, H. Chang, K. Pan, C. Tian and J. Zheng, Chem. Commun., 2015, 51, 14632 DOI: 10.1039/C5CC04846J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements