Graphene oxide quenches fluorescence corresponding to only a mismatched target due to selective denaturing of the thermo-unstable duplex composed of probe peptide nucleic acid and single base mismatched target RNA and thus, the fluorescence signal only from perfectly matched target RNA is measured.
J. Lee, G. Park and D. Min, Chem. Commun., 2015, 51, 14597 DOI: 10.1039/C5CC04706D
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