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Issue 61, 2015
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Design of a hyperpolarized 15N NMR probe that induces a large chemical-shift change upon binding of calcium ions

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Abstract

Ca2+ is a fundamental metal ion for physiological functioning. Therefore, molecular probes for Ca2+ analysis are required. Recently, a hyperpolarized NMR probe has emerged as a promising tool. Here, we report a new design of a hyperpolarized NMR probe for Ca2+, which showed a large chemical shift change upon binding to Ca2+ and was applied for Ca2+ sensing in a hyperpolarized state.

Graphical abstract: Design of a hyperpolarized 15N NMR probe that induces a large chemical-shift change upon binding of calcium ions

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Publication details

The article was received on 04 Jun 2015, accepted on 26 Jun 2015 and first published on 03 Jul 2015


Article type: Communication
DOI: 10.1039/C5CC04597E
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Citation: Chem. Commun., 2015,51, 12290-12292
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    Design of a hyperpolarized 15N NMR probe that induces a large chemical-shift change upon binding of calcium ions

    R. Hata, H. Nonaka, Y. Takakusagi, K. Ichikawa and S. Sando, Chem. Commun., 2015, 51, 12290
    DOI: 10.1039/C5CC04597E

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