Issue 67, 2015
From the journal:

Chemical Communications

A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry†

Selda Kabatas,‡a   Ingrid C. Vreja,‡bc   Sinem K. Saka,b   Carmen Höschen,d   Katharina Kröhnert,b   Felipe Opazo,b   Silvio O. Rizzoli*be  and  Ulf Diederichsen*ae  

* Corresponding authors

a Institute of Organic and Biomolecular Chemistry, University of Göttingen, Tammannstr. 2, D-37077 Göttingen, Germany
E-mail: udieder@gwdg.de

b Department of Neuro- and Sensory Physiology, University Medical Centre Göttingen, Humboldtallee 23, D-37073 Göttingen, Germany
E-mail: srizzol@gwdg.de

c International Max Planck Research School Molecular Biology, Göttingen, Germany

d Department of Ecology and Ecosystem Management, Centre of Life and Food Sciences Weihenstephan, Technische Universität München, Emil-Ramann-Straße 2, D-85354 Freising, Germany

e Centre for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany

Abstract

Imaging techniques should differentiate between specific signals, from the biomolecules of interest, and non-specific signals, from the background. We present a probe containing 15N and 14N isotopes in approximately equal proportion, for secondary ion mass spectrometry imaging. This probe designed for a precise biomolecule analysis is insensitive to background signals.

Graphical abstract: A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5CC03895B
Article type
Communication
Submitted
11 May 2015
Accepted
07 Jul 2015
First published
07 Jul 2015

Chem. Commun., 2015,51, 13221-13224

Permissions

Request permissions

A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry

S. Kabatas, I. C. Vreja, S. K. Saka, C. Höschen, K. Kröhnert, F. Opazo, S. O. Rizzoli and U. Diederichsen, Chem. Commun., 2015, 51, 13221 DOI: 10.1039/C5CC03895B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements