Issue 52, 2015
From the journal:

Chemical Communications

Controlled proliferation and screening of mammalian cells on a hydrogel-functionalized small molecule microarray†

Biwei Zhu,a   Bo Jiang,a   Zhenkun Naa  and  Shao Q. Yao*a  

* Corresponding authors

a Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore
E-mail: chmyaosq@nus.edu.sg

Abstract

A hydrogel-functionalized small molecule microarray has been developed, on which PC-3 cancer cells were selectively grown. Subsequent controlled release of immobilized bioactive compounds enabled cell-based screening to be directly carried out on this platform.

Graphical abstract: Controlled proliferation and screening of mammalian cells on a hydrogel-functionalized small molecule microarray

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Article information

DOI
https://doi.org/10.1039/C5CC03278D
Article type
Communication
Submitted
21 Apr 2015
Accepted
19 May 2015
First published
19 May 2015

Chem. Commun., 2015,51, 10431-10434

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Controlled proliferation and screening of mammalian cells on a hydrogel-functionalized small molecule microarray

B. Zhu, B. Jiang, Z. Na and S. Q. Yao, Chem. Commun., 2015, 51, 10431 DOI: 10.1039/C5CC03278D

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