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Issue 39, 2015
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Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

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Abstract

A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH˙) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH˙/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

Graphical abstract: Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

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Publication details

The article was received on 17 Mar 2015, accepted on 08 Apr 2015 and first published on 08 Apr 2015


Article type: Communication
DOI: 10.1039/C5CC02236C
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Citation: Chem. Commun., 2015,51, 8311-8314
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    Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

    I. Nakanishi, K. Ohkubo, K. Imai, M. Kamibayashi, Y. Yoshihashi, K. Matsumoto, K. Fukuhara, K. Terada, S. Itoh, T. Ozawa and S. Fukuzumi, Chem. Commun., 2015, 51, 8311
    DOI: 10.1039/C5CC02236C

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