Issue 44, 2015
From the journal:

Chemical Communications

Efficient construction of stable gene nanoparticles through polymerase chain reaction with flexible branched primers for gene delivery†

Jianbing Liu,a   Runyu Wang,a   Dejun Ma,a   Di Ouyanga  and  Zhen Xi*a  

* Corresponding authors

a Department of Chemical Biology, State Key Laboratory of Elemento-Organic Chemistry, National Engineering Research Center of Pesticide (Tianjin), Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin 300071, China
E-mail: zhenxi@nankai.edu.cn
Tel: +(86)-22-2350-4782

Abstract

Flexible branched primers were designed to construct stable gene nanoparticles with multiple target gene copies through polymerase chain reaction, which can be used as an efficient transcription template in eukaryotic cells for gene delivery.

Graphical abstract: Efficient construction of stable gene nanoparticles through polymerase chain reaction with flexible branched primers for gene delivery

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Article information

DOI
https://doi.org/10.1039/C5CC01788B
Article type
Communication
Submitted
02 Mar 2015
Accepted
28 Apr 2015
First published
28 Apr 2015

Chem. Commun., 2015,51, 9208-9211

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Efficient construction of stable gene nanoparticles through polymerase chain reaction with flexible branched primers for gene delivery

J. Liu, R. Wang, D. Ma, D. Ouyang and Z. Xi, Chem. Commun., 2015, 51, 9208 DOI: 10.1039/C5CC01788B

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